Guidance & Publications

AMRIC have consolidated all existing CPE guidance into one overall consolidated guidance document V1.0 Management and Control of Carbapenemase Producing Enterobacterales (CPE) in all Healthcare Settings as at 20.12.22.

Please note Guidelines for control and prevention of MDRO excl MRSA in healthcare setting is no longer available. It has been replaced by NCEC National Clinical Guideline No. 30 Infection Prevention and Control which is available at the following link   

Irish Guidance

International Guidance

ECDC Guidance - Infection prevention and control measures and tools for the prevention of entry of carbapenem-resistant Enterobacteriaceae into healthcare settings. Published 2017

WHO Guidance - Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa in health care facilities. Published 2017

Carbapenemase producing Enterobacteriaceae (CPE) Articles

Surveillance of CRE in Ireland - Epi Insight, Volume 18, Issue 2, February 2017

Enhanced surveillance of Carbapenem Resistant Enterobacteriaceae (CRE) in Ireland 2012 - Epi Insight, Volume 14, Issue 10, October 2013

Enhanced Surveillance of Carbapenem resistant Enterobacteriaceae (CRE) in Ireland: 2011 - Epi-Insight, Volume 13, Issue 12, December 2012

Carbapenemase-producing Enterobacteriaceae in Irish critical care units: results of a pilot prevalence survey, June 2011 - Journal of Hospital Infection, November 2012 [epublication ahead of print]

Isolation of NDM-1-producing Klebsiella pnemoniae in Ireland, July 2011 - Eurosurveillance, Volume 17, Issue 7, 16 February 2012

Study finds no CRE in Irish critical care units - Epi-Insight, Volume 12, Issue 10, October 2011

First isolation and outbreak of OXA-48-producing Klebsiella pneumoniae in an Irish hospital, March to June 2011 - Eurosurveillance, Volume 16, Issue 29, 21 July 2011

New study to detect prevalence of CRE hospital infection in Irish critical care units - Epi Insight, Volume 12, Issue 7, July 2011

CRE - update issued on laboratory detection and infection control measures - Epi Insight, Volume 12, Issue 5, May 2011

First identification of Class A carbapenemase-producing Klebsiella pneumoniae in the Republic of Ireland - Eurosurveillance, Volume 14, Issue 13, April 2009

Guidance for Control of Infections with Carbapenem-Resistant or Carbapenemase-Producing Enterobacteriaceae in Acute Care Facilities - MMWR, Volume 58, Issue 10, March 2009

Advice on Carbapenemase Producers: Recognition, infection control and treatment - HPA, UK

Laboratory Protocol for Detection of Carbapenem-Resistant or Carbapenamase-Producing, Klebsiella spp. and E. coli from Rectal Swabs - CDC, US

First identified case of VIM-producing Cabapenem-Resistant Klebsiella pneumoniae in the Republic of Ireland associated with fatal outcome - Eurosurveillance, Volume 15, Issue 50, December 2010 

Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control - Clinical Microbiology and Infection, Volume 16, Number 2, February 2010

Last updated: 13 February 2017