Leptospirosis (Leptospira species)

Clinical criteria
Any person with
- Fever
OR
At least two of the following eleven:
- Chills
- Headache
- Myalgia
- Conjunctival suffusion
- Haemorrhages into skin and mucous membranes
- Rash
- Jaundice
- Myocarditis
- Meningitis
- Renal impairment
- Respiratory symptoms such as haemoptysis

Laboratory criteria
At least one of the following four:
- Isolation of Leptospira interrogans or any other pathogenic Leptospira spp from a clinical specimen
- Detection of Leptospira interrogans or any other pathogenic Leptospira spp nucleic acid in a clinical specimen
- Demonstration of Leptospira interrogans or any other pathogenic Leptospira spp by immunofluorescence in a clinical specimen
- Leptospira interrogans or any other pathogenic Leptospira spp specific antibody response

Epidemiological criteria
An epidemiological link by exposure to a common source

Case classification
A. Possible case
NA
B. Probable case
Any person meeting the clinical criteria and with an epidemiological link
C. Confirmed case
Any person meeting the clinical and the laboratory criteria

Current as of: 7 March 2019