Integrated Respiratory Virus Bulletin, Ireland

Week 44 2024 (27/10/2024 - 03/11/2024)

Report prepared on 07/11/2024



This interactive bulletin reports on the latest epidemiology of COVID-19, influenza, respiratory syncytial virus (RSV) and other respiratory viruses (ORVs) in Ireland. HPSC monitors several integrated respiratory virus surveillance systems that are included in this bulletin. This report will be published weekly during the winter season (week 40 to week 20).

How to use this interactive bulletin

For interactive graphs – data values and labels can be seen by hovering over graph lines or bars. Specific categories can be selected or deselected by clicking on the relevant category in the legend. Readers can skip to specific sections by clicking on the table of contents to the left of the screen.

1 Key messages

During week 44 2024, influenza remained stable and RSV activity increased, although the numbers of reported cases remain relatively low. COVID-19 activity increased. Rhinoviruses and enteroviruses are circulating at high levels. Other seasonal respiratory viruses remain at low levels.

1.1 Summary for week 44 2024

Primary Care Surveillance

The sentinel GP Acute Respiratory Infection (ARI) consultation rate declined, for the second week in a row, to 43.9/100,000 population during week 44, compared to 64.4/100,000 in week 43. Sentinel percentage positivity for rhinovirus or enterovirus was 24.3% in week 44. Rhino or enterovirus positivity has been above the 10% positivity threshold since week 35 2024. All other respiratory pathogens remain below the threshold. The proportion of GPOOH calls for self-reported cough increased for all age-groups and was over the threshold overall and for those aged <15 years in week 44. Calls for self-reported flu cases remain below the threshold.

COVID-19

COVID-19 activity increased across all indicators in week 44. COVID-19 cases increased by 25.3% from 249 cases notified in week 43 to 312 cases in week 44. Hospitalised cases increased by 36.1%, with 132 cases in week 44 compared to 97 cases in week 43. This increase may be partly due to delayed notifications in week 44. ICU admissions and deaths remained low. KP.3.1.1 is the dominant sub-lineage, accounting for 43.5% of samples sequenced between weeks 37 and 42, 2024. Emerging variant XEC continues to increase and accounted for 20.6% of sequences in the same time period. SARS-CoV-2 viral loads in wastewater decreased in most catchment areas in week 44 2024.

Influenza

Influenza activity remained stable in week 44 2024. The overall notification rate was 1.5/100,000 population, and was highest in those aged less than one year. There were 79 cases (a slight decrease from 91 cases reported in week 43), 25 hospitalisations, no ICU cases and no deaths reported. Influenza A virus is currently the dominant type accounting for 92% of cases.

RSV

RSV activity increased in week 44 but numbers of reported cases remain low. The overall notification rate was 0.8/100,000 population and was highest in those aged less than one year at 20.8/100,000 population. There were 39 cases (compared to 29 reported in week 43), 22 hospitalisations, no ICU admissions and no deaths reported. The number of notified and hospitalised cases remain low in all age groups.

Severe Acute Respiratory Infection (SARI)

Based on data from the three sentinel hospital sites, although SARI case numbers remained stable in week 44, with 58 cases reported (same as the previous week), the incidence of SARI cases amongst total hospital admissions (via emergency departments) increased by 33% due to an increase amongst adult cases. In week 44, influenza positivity increased to 14.6%, with no influenza positive cases reported in week 43, while RSV increased slightly to 7.1% from 6.4%, while SARS-CoV-2 positivity decreased to 2.4% from 14.9% in week 43.

Outbreaks

COVID-19 outbreaks increased by 20% in week 44 compared to week 43 2024. A total of 18 COVID-19 outbreaks were reported including five in hospitals and nine in nursing homes. During week 44, one influenza A outbreak and five other ARI outbreaks were reported in nursing homes. No RSV outbreaks were reported.


2 Activity

2.1 Confirmed Cases


1: Number of notified cases of laboratory confirmed of COVID-19, influenza and RSV by notification week in Ireland between week 40 2023 and week 44 2024. Data source: CIDR


Table 1: Number and incidence of notified cases of laboratory confirmed cases COVID-19, influenza and RSV, by age, sex and HSE health region, Ireland, week 44 2024. Data source: CIDR.

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

430 (8.4)

312 (6.1)

79 (1.5)

39 (0.8)

Age groups (years)

<1

21 (36.3)

6 (10.4)

3 (5.2)

12 (20.8)

1-4

32 (13.5)

5 (2.1)

10 (4.2)

17 (7.2)

5-14

20 (2.8)

1 (0.1)

18 (2.5)

1 (0.1)

15-44

60 (2.9)

43 (2.1)

14 (0.7)

3 (0.1)

45-64

79 (6.1)

63 (4.9)

16 (1.2)

0 (0.0)

65-79

97 (16.3)

85 (14.3)

10 (1.7)

2 (0.3)

>80

121 (66.8)

109 (60.2)

8 (4.4)

4 (2.2)

Median age (IQR)

65 (34-81)

72 (53-82)

33 (8-60)

1 (0-6)

Sex

Male

192 (7.5)

122 (4.8)

45 (1.8)

25 (1.0)

Female

238 (9.1)

190 (7.3)

34 (1.3)

14 (0.5)

HSE Health Regions

Dublin and North East

126 (2.4)

114 (9.6)

5 (0.4)

7 (0.6)

Dublin and Midlands

75 (1.5)

54 (5)

18 (1.7)

3 (0.3)

Dublin and South East

103 (2)

72 (7.4)

20 (2.1)

11 (1.1)

South West

38 (0.7)

27 (3.6)

10 (1.4)

1 (0.1)

Mid West

20 (0.4)

10 (2.4)

6 (1.5)

4 (1)

West and North West

68 (1.3)

35 (4.6)

20 (2.6)

13 (1.7)


An overview of the characteristics of all cases reported since the start of the season is presented in Appendix A1.


2: Incidence of notified cases of laboratory-confirmed COVID-19, influenza and RSV by HSE Health Region for the last 12 weeks, from week 32 2024 to week 44 2024. Data source: CIDR


3: A: Age and sex-specific incidence of notified cases of laboratory confirmed COVID-19, influenza and RSV from week 40 2024 to week 44 2024. Data source: CIDR


Please note that the scale on the x-axis may differ by pathogen, to account for differences in the number of cases notified for each pathogen.


4: Incidence of notified cases of laboratory confirmed COVID-19, influenza and RSV by age group from week 40 2023 to week 44 2024. Data source: CIDR


2.2 Sentinel GP Acute Respiratory Infection (ARI) Surveillance

2.2.1 Sentinel GP ARI

5: Sentinel GP ARI consultation rate per 100,000 population overall (with associated number of influenza, RSV and SARS-CoV-2 positive sentinel GP ARI specimens) from week 40 2023 to week 44 2024

2.2.2 Sentinel GP ARI by Age Group

6: Sentinel GP ARI consultation incidence by age-group, from week 40 2023 to week 44 2024 2024


2.3 GP Out-of-Hours Surveillance


7: Percentage of calls to GP Out-of-Hours services for self-reported cough and self-reported flu, for all ages and by age-group, by week of call from week 40 2023 to week 44 2024. Source: Participating GP Out-of-Hours services in Ireland.


3 Severity and Impact

3.1 Emergency Department Cases

3.1.1 Incidence of Emergency Department Cases

8: Incidence of emergency department cases of laboratory confirmed COVID-19, influenza and RSV emergency department cases from week 40 2023 to week 44 2024. Data source: CIDR


3.1.2 Number of Emergency Department Cases


9: Number of emergency department cases of laboratory confirmed COVID-19, influenza and RSV, from week 40 2023 to week 44 2024. Data source: CIDR


3.2 Hospital Admissions

3.2.1 Incidence of Hospitalised Cases


10: Incidence of hospitalised cases of laboratory confirmed COVID-19, influenza and RSV from week 40 2023 to week 44 2024. Data source: CIDR


3.2.2 Number of Hospitalised Cases


11: Number of hospitalised cases of laboratory confirmed COVID-19, influenza and RSV from week 40 2023 to week 44 2024. Data source: CIDR


Table 2: Number and incidence of hospitalised cases of laboratory confirmed COVID-19, influenza and RSV by age, sex and HSE health region, Ireland, week 44 2024. Data source: CIDR

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

179 (3.5)

132 (2.6)

25 (0.5)

22 (0.4)

Age groups (years)

<1

14 (24.2)

4 (6.9)

2 (3.5)

8 (13.8)

1-4

17 (7.2)

2 (0.8)

5 (2.1)

10 (4.2)

5-14

10 (1.4)

1 (0.1)

8 (1.1)

1 (0.1)

15-44

16 (0.8)

15 (0.7)

0 (0.0)

1 (0.0)

45-64

24 (1.9)

21 (1.6)

3 (0.2)

0 (0.0)

65-79

44 (7.4)

40 (6.7)

3 (0.5)

1 (0.2)

>80

54 (29.8)

49 (27.1)

4 (2.2)

1 (0.6)

Median age (IQR)

69 (29-81)

74 (58.5-83)

9 (4-68)

1 (0-2.75)

Sex

Male

86 (3.4)

57 (2.2)

16 (0.6)

13 (0.5)

Female

93 (3.6)

75 (2.9)

9 (0.3)

9 (0.3)

HSE Health Regions

Dublin and North East

55 (1.1)

51 (4.3)

0 (0)

4 (0.3)

Dublin and Midlands

27 (0.5)

19 (1.8)

7 (0.6)

1 (0.1)

Dublin and South East

36 (0.7)

23 (2.4)

6 (0.6)

7 (0.7)

South West

13 (0.3)

11 (1.5)

1 (0.1)

1 (0.1)

Mid West

11 (0.2)

5 (1.2)

3 (0.7)

3 (0.7)

West and North West

37 (0.7)

23 (3)

8 (1.1)

6 (0.8)


An overview of the characteristics of all hospitalised cases reported since the start of the season is presented in Appendix A2.


12: Age and sex-specific incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV from week 40 2024 to week 44 2024. Data source: CIDR


13: Incidence of hospitalised cases of laboratory confirmed COVID-19, influenza and RSV by age group from week 40 2023 to week 44 2024. Data source: CIDR


Figure 14: Cumulative incidence of hospitalised cases of laboratory confirmed COVID-19, influenza and RSV by HSE health region, according to patient county of residence in week 44 2024. Data source: CIDR


Table 3: Number and incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV by HSE Health region (according to patient county of residence) for week 44 2024. Data source: CIDR

HSE region

COVID-19

Influenza

RSV

Number of cases

Incidence per 100,000 population

Number of cases

Incidence per 100,000 population

Number cases

Incidence per 100,000 population

Dublin and North East

51

4.3

0

0.0

4

0.3

Dublin and Midlands

19

1.8

7

0.6

1

0.1

Dublin and South East

23

2.4

6

0.6

7

0.7

South West

11

1.5

1

0.1

1

0.1

Mid West

5

1.2

3

0.7

3

0.7

West and North West

23

3.0

8

1.1

6

0.8

Total

132

2.6

25

0.5

22

0.4


3.2.3 Bed Occupancy in Acute Inpatient Settings


15: Number of hospital beds occupied by patients with laboratory confirmed COVID-19, influenza or RSV. Data source: HSE Planning and Performance Unit


3.3 ICU Admissions


16: Number of ICU admissions due to laboratory-confirmed COVID-19, influenza and RSV, week 40 2023 to week 44 2024. Data source: CIDR


Table 4: Number and incidence of ICU admissions due to COVID-19, influenza and RSV, week 44 2024, and season to date (from week 40 2024). Data source: CIDR.

Week 44, 2024

Season to date

Number of ICU admissionsa

ICU admissions per 1,000 hospitalisations

% of hospitalised cases admitted to ICU

Number of ICU admissions

ICU admissions per 1,000 hospitalisations

% of hospitalised cases admitted to ICU

COVID-19

0

0

0

13

19.1

1.9

Influenza

0

0

0

1

10.3

1.0

RSV

0

0

0

3

49.2

4.9

aICU admissions include all cases admitted to ICU due to COVID-19, influenza and RSV.


3.4 Sentinel Severe Acute Respiratory Infection (SARI) Surveillance


17: Number and incidence of SARI hospitalised cases (emergency admissions) by week of hospital admission, from week 40 2023 to week 44 2024. Data source: Sentinel SARI surveillance system.


18: Percentage of SARI cases with a positive laboratory test result for SARS-CoV-2, influenza and RSV by week, from week 40 2023 to week 44 2024. Data source: Sentinel SARI surveillance system.


3.5 Mortality

3.5.1 Deaths Among Confirmed Cases


19: Number of COVID-19, influenza and RSV deaths by week of death. Data source: CIDR


Table 5: Number and incidence of COVID-19, influenza and RSV deaths for the season to date. Data source: CIDR

COVID-19

Influenza

RSV

Age (years)

Number

Incidence per 100,000 population

Number

Incidence per 100,000 population

Number

Incidence per 100,000 population

<65

0

0.0

0

0.0

0

0

>65

18

2.3

1

0.1

0

0

Total

18

0.3

1

0.0

0

0


4 Outbreaks


20: Number of COVID-19, influenza, RSV and other ARI outbreaks reported in health and care settings from week 40 2023 to week 44 2024


Table 6 : COVID-19, influenza, RSV and other ARI outbreaks reported by setting week 44 2024. Data source: CIDR

Epi week: 44 2024

Outbreak location

COVID-19

Influenza

RSV

ARI

Total week 44, 2024

Total season to date

Comm. Hosp/Long-stay unit

1

0

0

0

1

8

Hospital

5

0

0

0

5

50

Nursing home

9

1

0

3

13

59

Other healthcare service

0

0

0

0

0

6

Residential institution

3

0

0

2

5

21

Total Health Care Settings

18

1

0

5

24

144

Total Non Health Care Settings

0

0

0

0

0

1

Total

18

1

0

5

24

145


21: Number of COVID-19, influenza, RSV and other ARI outbreaks by HSE health region, week 44 2024


5 Virology and Genomic Surveillance

5.1 Virus Positivity and Dominant Virus Types/subtypes in Circulation


Table 7: Number and percentage positive SARS-CoV-2, influenza and RSV specimens by surveillance source, week 44 2024. Data source: CIDR, National Virus Reference Laboratory (NVRL) and St. Vincent’s University Hospital (SVUH).

SARS-CoV-2

Influenza

RSV

Surveillance system

Total tested

Total positive

% positive

Total positive

% positive

Total positive

% positive

NVRL Sentinel GP ARI

37

1

2.7

1

2.7

0

0

NVRL nonsentinel respiratory viruses

101

7

6.9

1

1.0

4

4

SARS-CoV-2 Laboratory-based surveillance

2,726

173

6.3


22: Percentage for sentinel GP ARI specimens and non-sentinel respiratory specimens testing positive for SARS-CoV-2, influenza, RSV and other respiratory viruses, by week of specimen collection, week 20 2024 to week 44 2024. PIV = parainfluenza viruses. hMPV = human metapneumovirus. Data source: NVRL


23: Number of sentinel GP ARI and non-sentinel respiratory influenza positive specimens, and laboratory confirmed influenza notifications by influenza type/sub-type, by week of specimen collection, week 40 2023 to week 44 2024. Data source: NVRL, CIDR


Underlying data on the total number of tests, total number of positives and percentage positive by week and for the season to date for each virus for both sentinel and non-sentinel specimens are presented in Appendix A3, Appendix A4, Appendix A5, Appendix A6


5.2 SARS-CoV-2 Genetic and Antigenic Data Including Whole Genome Sequencing


24: SARS-CoV-2 whole genome sequencing results, specimen collection dates from week 14 2023 to week 42 2024


There is typically a lag time of 1-3 weeks between a case being notified, selected for sequencing and sequencing being completed. Therefore the percentage of cases notified in this time period who are ultimately sequenced will be higher than reported here.


25: SARS-CoV-2 whole genome sequencing results by week specimen collected from week 38 2024 to week 42 2024


6 SARS-CoV-2 Wastewater Surveillance


26: Approximate location of wastewater catchment areas and SARS-CoV-2 viral loads (gc/day) in wastewater and percentage change compared to previous week, National Wastewater Surveillance Programme, week 44 2024


Figure 27: Weekly distribution of population-normalised SARS-CoV-2 viral load (gc/day/person), National Wastewater Surveillance Programme, week 19 2021 to week 44, 2024


9 Technical notes

General

Data are provisional and subject to ongoing review, validation and update. As a result, figures in this report may differ from previously published figures.

The weekly calendar runs from Sunday to Saturday for respiratory virus notifications on CIDR (as per the Infectious Disease Regulations 1982 and subsequent amendments) and Monday to Sunday for the sentinel GP and SARI surveillance systems (as per ISO week). Further information on epidemiological dates and weeks can be found on the HPSC website.

Definitions

The case definitions for COVID-19, influenza and RSV are available here. Only data on laboratory-confirmed cases, including cases diagnosed using near patient molecular tests, are included in this report.

Sentinel GP ARI consultations are consultations to sentinel GP practices for Acute Respiratory Infection (ARI), with ARI defined as Sudden onset of symptoms AND at least one of the following four respiratory symptoms: Cough, sore throat, shortness of breath, coryza AND a clinician’s judgement that the illness is due to an infection.

GP out of hours calls refer to calls to GP out of hours services from persons with self-reported clinical symptoms of ‘flu’ or ‘cough’.

Emergency Department cases refer to cases treated in emergency departments, with no indication on CIDR that they have subsequently been admitted to hospital.

Hospitalised cases are inpatients with laboratory confirmed SARS-CoV-2, influenza or RSV and includes inpatients with incidental infections, where the infection is not the reason for their admission.

Bed occupancy refers to the number of laboratory confirmed cases admitted to acute inpatient sites at 08:00 hrs on the day of reporting.

A SARI case is defined as a person hospitalised for at least 24 hours with acute respiratory infection, with at least one of the following symptoms: cough, fever, shortness of breath OR sudden onset of anosmia, ageusia or dysgeusia with onset of symptoms within 14 days prior to hospital admission. A SARI case refers to an individual patient episode of care.

As of September 2024, ICU admissions for COVID-19, influenza and RSV refer to those admitted to intensive care where COVID-19, influenza or RSV were the primary or contributory cause of admission. Prior to September 2024, ICU admissions for influenza and RSV included all admissions where the patient tested positive for influenza or RSV, irrespective of whether these pathogens were the cause of admission.

COVID-19, influenza and RSV deaths are defined as a death in a person with laboratory confirmed COVID-19, influenza or RSV infection see case definitions (this includes cases detected postmortem) and where COVID-19, influenza or RSV is reported in any of the four cause of death fields on the death certificate. Deaths where there is a clear alternative cause of death (e.g. trauma, suicide) are not recorded as COVID-19/influenza/RSV deaths. Deaths where there is a period of complete recovery (as assessed by a clinician) between a COVID-19, influenza or RSV episode of illness and death, are also not recorded as deaths.

Test Positivity: Positive tests refer to all positive specimens and includes duplicates and individuals who were re-tested.

Outbreaks are defined as two or more cases of acute respiratory infection with the same pathogen (SARS-CoV-2, influenza or respiratory syncytial virus (RSV)) confirmed by a laboratory test or near patient test carried out by a health professional, and where there is reason to consider that these cases may be epidemiologically linked in place and time.

Other Acute Respiratory Infection (ARI) outbreaks are defined as: Two or more cases of acute respiratory infection arising within the same 48hr period epidemiologically linked in place: Outbreaks are classified as Suspect ARI outbreaks, where testing has not been completed, is pending or has been negative for Influenza, RSV and SARS-CoV-2. Outbreaks are classified as confirmed if other respiratory pathogens (ORVs), e.g. Rhinovirus, hMPV, Coronavirus OC43 etc are identified via laboratory confirmation. The outbreak data presented in this report includes both confirmed and suspect outbreaks.

Variant working definitions for ‘SARS-CoV-2 variants of concern’ (VOC), ‘SARS-CoV-2 variants of interest’ (VOI) and ‘SARS-CoV-2 variants under monitoring’ (VUM) are available on the WHO website and ECDC website.

Data Sources

The Computerised Infectious Disease Reporting (CIDR) system: CIDR is the source of statutory notification data on laboratory-confirmed COVID-19, influenza, RSV (including data on notified, emergency department, hospitalised and ICU cases and data on cases who died) and data on outbreaks.

The type/subtype of laboratory confirmed influenza notifications are reported on the CIDR system. The number of cases hospitalised and admitted to ICU described in this report relate only to cases notified during this reporting period, with known hospitalisation/ICU status at the time of reporting.

Regional Departments of Public Health currently prioritise the investigation and reporting of outbreaks in settings that benefit most from public health and clinical intervention. The outbreak data reported here focuses on these key settings/groups. These settings include acute hospitals, nursing homes, community hospital/long-stay units, residential institutions (centres for disabilities, centres for older people, children’s/TUSLA residential centres and mental health facilities) and other healthcare settings.

Population denominator data for analyses of CIDR data on notified, emergency department, hospitalised and ICU cases and deaths are taken from Census 2022.

Sentinel GP surveillance system: This includes 100 participating general practices (located in all HSE Health Regions). These practices report electronically on a weekly basis, the number of patients who consulted with acute respiratory infection (ARI) and influenza-like illness (ILI) (identified using International Classification of Primary Care 2 codes R74 and R80). These practices provide overall and age-stratified denominator data on the number of registered patients who have sought care at the practice during the previous three years. The combined patient population in these practices is estimated to be approximately 10% of the national population. Sentinel GPs take a combined nose and throat swab from the first five patients attending their practice each week who meet the ARI case definition and send these to the NVRL for testing.

GP Out-of-hours (GPOOHs) services: Five out of 14 GPOOHs services provide weekly data on the total and age-stratified number of out of hours calls for 1) all reasons, 2) for self-reported cough and 3) for self-reported flu. The denominator for calculations of percentage of calls is the total number of calls for all reasons.

The HSE Performance Management and Improvement Unit (PMIU) provides daily data on bed occupancy (the number of currents inpatients with laboratory confirmed COVID-19, influenza and RSV).

Severe Acute Respiratory Infections (SARI) surveillance system: SARI cases are identified from new admissions through the Emergency Department, based on clinical symptoms. Patients that develop SARI during their admission, or who are admitted through alternate routes, are not included.

National Virus Reference Laboratory (NVRL): The NVRL routinely test sentinel GP and non-sentinel respiratory specimens for SARS-CoV-2, influenza, RSV and a panel of other seasonal respiratory viruses (ORV). The NVRL report on influenza type/subtype of sentinel GP ARI and non-sentinel respiratory specimens on a weekly basis.

National SARS-CoV-2 Whole Genome Sequencing Surveillance Programme (NSWGSSP): The SARS-CoV-2 sequencing sampling framework currently focuses on notified COVID-19 cases with severe disease (hospitalisation, ICU admission) and deaths, COVID-19 outbreaks in health and care settings, sentinel surveillance programmes in the community and acute hospitals and targeted sequencing based on public health risk assessment/clinical requests and virological changes e.g. new variant of concern. There is typically a lag time of 1-3 weeks between a COVID-19 case being notified, selected for sequencing and SARS-CoV-2 sequencing being completed. Therefore, the proportion of notified COVID-19 cases notified in this time period from whom specimens are ultimately sequenced will be higher than currently reported here. The HPSC link sequencing results received from laboratories to epidemiological data on COVID-19 cases reported on the CIDR system. This report summarises WGS results and epidemiological data for COVID-19 cases that have been sequenced in Ireland since week 51 2020 (specimen dates between 13/12/2020 and 27/09/2024). The SARS-CoV-2 sequencing results included in this report reflect all data available as of 14/10/2024.

National SARS-CoV-2 Wastewater Surveillance Programme: A detailed description of the process involved for wastewater collection, sampling and analyses is available in the routinely published national SARS-CoV-2 wastewater surveillance programme reports available here


10 Appendix

Appendix Table 1: Notified laboratory confirmed cases of COVID-19, influenza and RSV by age, sex and HSE health region, from week 40 2024, to week 44 2024. Data source: CIDR.

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

2,046 (39.7)

1,629 (31.6)

302 (5.9)

115 (2.2)

Age groups (years)

<1

100 (173.0)

66 (114.2)

7 (12.1)

27 (46.7)

1-4

111 (46.7)

31 (13.0)

36 (15.2)

44 (18.5)

5-14

78 (10.9)

19 (2.7)

55 (7.7)

4 (0.6)

15-44

289 (14.0)

217 (10.5)

63 (3.0)

9 (0.4)

45-64

386 (29.8)

318 (24.6)

61 (4.7)

7 (0.5)

65-79

492 (82.6)

443 (74.4)

41 (6.9)

8 (1.3)

>80

590 (325.9)

535 (295.5)

39 (21.5)

16 (8.8)

Median age (IQR)

68 (40-81)

72 (51-82)

40 (9-68)

2 (1-56)

Sex

Male

975 (38.3)

763 (30.0)

157 (6.2)

55 (2.2)

Female

1,070 (41.1)

866 (33.2)

145 (5.6)

59 (2.3)

HSE Health Regions

Dublin and North East

435 (8.4)

379 (31.9)

39 (3.3)

17 (1.4)

Dublin and Midlands

346 (6.7)

271 (25.1)

59 (5.5)

16 (1.5)

Dublin and South East

447 (8.7)

364 (37.5)

57 (5.9)

26 (2.7)

South West

321 (6.2)

262 (35.4)

57 (7.7)

2 (0.3)

Mid West

168 (3.3)

128 (31)

24 (5.8)

16 (3.9)

West and North West

329 (6.4)

225 (29.6)

66 (8.7)

38 (5)


Appendix Table 2: Hospitalised laboratory confirmed cases of COVID-19, influenza and RSV by age, sex and HSE health region, from week 40,2024, to week 44 2024. Data source: CIDR.

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

839 (16.3)

681 (13.2)

97 (1.9)

61 (1.2)

Age groups (years)

<1

48 (83.1)

25 (43.3)

5 (8.7)

18 (31.1)

1-4

49 (20.6)

15 (6.3)

13 (5.5)

21 (8.8)

5-14

44 (6.1)

13 (1.8)

27 (3.8)

4 (0.6)

15-44

70 (3.4)

59 (2.9)

8 (0.4)

3 (0.1)

45-64

125 (9.7)

109 (8.4)

11 (0.9)

5 (0.4)

65-79

220 (37.0)

200 (33.6)

15 (2.5)

5 (0.8)

>80

283 (156.3)

260 (143.6)

18 (9.9)

5 (2.8)

Median age (IQR)

72 (44-83)

75 (59-84)

29 (7-74)

2 (0-36)

Sex

Male

430 (16.9)

343 (13.5)

56 (2.2)

31 (1.2)

Female

409 (15.7)

338 (13.0)

41 (1.6)

30 (1.2)

HSE Health Regions

Dublin and North East

110 (2.1)

93 (7.8)

7 (0.6)

10 (0.8)

Dublin and Midlands

149 (2.9)

121 (11.2)

20 (1.9)

8 (0.7)

Dublin and South East

143 (2.8)

114 (11.7)

14 (1.4)

15 (1.5)

South West

145 (2.8)

128 (17.3)

16 (2.2)

1 (0.1)

Mid West

89 (1.7)

70 (16.9)

9 (2.2)

10 (2.4)

West and North West

203 (3.9)

155 (20.4)

31 (4.1)

17 (2.2)


Appendix Table 3: Number and percentage positive Sentinel GP ARI specimens by respiratory virus, for week 43 2024, week 44 2024, and the 2024/2025 season. Data source: NVRL.

Week 43 2024 (N = 106)

Week 44 2024 (N = 37)

2024/2025 (N = 496)

Virus

Total positive

% positive

Total positive

% positive

Total positive

% positive

SARS-CoV-2

8

7.5

1

2.7

30

6.0

Influenza Virus

6

5.7

1

2.7

22

4.4

Respiratory Syncytial Virus (RSV)

2

1.9

0

0.0

4

0.8

Rhino/enterovirus

29

27.4

9

24.3

141

28.4

Adenovirus

2

1.9

0

0.0

4

0.8

Bocavirus

1

0.9

0

0.0

4

0.8

Human metapneumovirus (hMPV)

0

0.0

0

0.0

0

0.0

Parainfluenza virus type 1 (PIV-1)

0

0.0

3

8.1

8

1.6

Parainfluenza virus type 2 (PIV-2)

2

1.9

0

0.0

9

1.8

Parainfluenza virus type 3 (PIV-3)

1

0.9

1

2.7

5

1.0

Parainfluenza virus type 4 (PIV-4)

0

0.0

0

0.0

4

0.8


Appendix Table 4: Number and percentage positive NVRL non-sentinel respiratory specimens by respiratory virus, week 43 2024, week 44 2024, and the 2024/2025 season. Data source: NVRL.

Week 43 2024 (N = 97)

Week 44 2024 (N = 101)

2024/2025 (N = 727)

Virus

Total positive

% positive

Total positive

% positive

Total positive

% positive

SARS-CoV-2

8

8.2

7

6.9

51

7.0

Influenza Virus

8

8.2

1

1.0

31

4.3

Respiratory Syncytial Virus (RSV)

2

2.1

4

4.0

7

1.0

Rhino/enterovirus

25

25.8

22

21.8

176

24.2

Adenovirus

4

4.1

2

2.0

12

1.7

Bocavirus

3

3.1

2

2.0

9

1.2

Human metapneumovirus (hMPV)

0

0.0

0

0.0

0

0.0

Parainfluenza virus type 1 (PIV-1)

1

1.0

4

4.0

14

1.9

Parainfluenza virus type 2 (PIV-2)

4

4.1

2

2.0

11

1.5

Parainfluenza virus type 3 (PIV-3)

0

0.0

0

0.0

0

0.0

Parainfluenza virus type 4 (PIV-4)

4

4.1

2

2.0

9

1.2


Appendix Table 5: Influenza type and sub-type distribution among sentinel GP ARI and non-sentinel respiratory influenza positive specimens, for week 43 2024, week 44 2024, and the 2024/2025 season. Data source: NVRL.

Influenza A

Influenza B

Time period

Specimen source

Total influenza positive

Total

A(H1)pdm09

A(H3)

A(not subtyped)

Total

B Victoria

B (upspecified)

Week 43 2024

Sentinel GP ARI

6

6

3

2

1

0

0

0

Non-sentinel respiratory

8

7

0

6

1

1

0

1

Total

14

13

3

8

2

1

0

1

Week 44 2024

Sentinel GP ARI

1

1

1

0

0

0

0

0

Non-sentinel respiratory

1

0

0

0

0

1

0

1

Total

2

1

1

0

0

1

0

1

Season to date

Sentinel GP ARI

22

22

11

9

2

0

0

0

Non-sentinel respiratory

31

25

15

8

2

6

0

6

Total

53

47

26

17

4

6

0

6


Appendix Table 6: RSV type distribution among sentinel GP ARI and non-sentinel respiratory RSV positive specimens, for week 43, 2024 week 44 2024, and the 2024/2025 season. Data source: NVRL.

Time period

Specimen source

Total RSV positive

RSV A

RSV B

RSV (unspecified)

Week 43 2024

Sentinel GP ARI

2

1

1

0

Non-sentinel respiratory

2

1

1

0

Total

4

2

2

0

Week 44 2024

Sentinel GP ARI

0

0

0

0

Non-sentinel respiratory

4

1

3

0

Total

4

1

3

0

Season to date

Sentinel GP ARI

4

2

2

0

Non-sentinel respiratory

7

3

4

0

Total

11

5

6

0